May has smootched Ed many times. She even gave him a Valentine's Day card but he just ran away. He has also tried to fool the Kanker sisters many times.
The boy Marie Kanker has claimed as her own and makes sure everyone knows it. He probably protests the most out of his friends when advanced by a Kanker, and is usually the one to sound the alarm. Despite this inate fear, he is also the most level headed when dealing with the Terrible Trio, knowing just how to bribe each one of the sisters best (usually with either money or tator tots.)
Eddy downright hates the Kanker Sisters. In "Ed, Edd, Eddy, n Eddy" things get more confusing for him when Edna befriends May and despite saving his life, he doesn't trust her but his friends still give him time.
In "Run For Your Ed", the Kankers tear up the Cul-De-Sac, leading the frightened neighborhood kids to run and hide in terror.
In canon, the Kankers tied him to a tire and asked him ridiculous questions such as "What color is your underwear?"
Only two Kankers have a conflict with Edna, as she is best friends with May. However this has changed when the Killer Sisters invaded Peach Creek just to do away with the Kankers due to a unexplored rivalry. May, Edna and the male Eds belive not even Lee and Marie deserve this so they formed a truce to eliminate those three.
Molly and Sandy
It shows that they don't like the Kankers. In one episode of Ed, Edd n Eddy's Brand New Show! the Kankers kidnap Sandy.
|"The space beneath the rock is vacant."-- Rolf
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