The Destruction of Rathink Avenue: The Sequel is the sequel to an event that happened in the canon Ed, Edd n Eddy episode "Run for your Ed". It involves the Kanker Sisters finding out that their prized new Hubcaps Digest magazine has been stolen, and, just like their Ship-In-A-Bottle, they want it back, and will go on a warpath again to find it.
Chapter 1: The Kanker Sisters wake up and start making their breakfast, and check their front porch to see if their new Hubcaps Digest magazine has arrived. It did, but someone ripped open the packaging and stole it! The Kankers are enraged, and prepare to wreck through the cul-de-sac to find it and who stole it.
Chapter 2: The Eds are working on their next scam and among their supplies is the Kanker's Ship-In-A-Bottle. Unfortunately, they don't know that it belongs to them. The Kankers have now arrived at the cul-de-sac and are beginning to wreck havoc, and desperately are trying to locate their Hubcaps Digest magazine.
Chapter 3: The Kankers destroy the cul-de-sac and tie up most of the kids. They still did not find their magazine. Houses are damaged or demolished and debris is scattered all over the cul-de-sac. Edd and Eddy, who were not tied up, now must rescue the rest of the kids.
Chapter 4: The Eds now untie all of the neighborhood kids. They look over the damage that had swept through the cul-de-sac and wonder what is to be done about it. The Kankers eventually return to the cul-de-sac and demand that the Eds show them where the Hubcaps Digest magazine is. The Eds give it back to the Kankers and somehow avoid a huge conflict. The cul-de-sac lies in ruins, damaged beyond repair.